2021年 
Yamamoto S, Okamura K, Fujii R, Kawano T, Ueda K, Yajima Y, Shiba K
Specimen-specific drift of densities defines distinct subclasses of extracellular vesicles from human whole saliva
PLoS One 16: e0249526 (2021)

Watanabe M, Bhawal UK, Takemoto S, Nishiyama N, Nakahara Y, Tatematsu KI, Sezutsu H, Kuwabara N, Minamisawa T, Shiba K, Asakura T
Label-free chemical imaging flow cytometry by high-speed multicolor stimulated Raman scattering
Biotechnol Bioeng 118: 2585-2596 (2021)

Hiraga C, Yamamoto S, Hashimoto S, Kasahara M, Minamisawa T, Matsumura S, Katakura A, Yajima Y, Nomura T, Shiba K
Pentapartite fractionation of particles in oral fluids by differential centrifugation
Sci Rep 11: 3326 (2021)
総説・解説など

平賀智豊、野村武史、芝 清隆
唾液とリキッドバイオプシー
歯界展望 138: 192-196(2021)


2020年 
Sonoda T, Yanagitani N, Suga K, Yoshizawa T, Nishikawa S, Kitazono S, Horiike A, Shiba K, Ishizuka T, Nishio M, Matsusaka S
Label-free chemical imaging flow cytometry by high-speed multicolor stimulated Raman scattering
Anticancer Res 40: 5577-5582 (2020)

Nitta N, Iino T, Isozaki A, Yamagishi M, Kitahama Y, Sakuma S, Suzuki Y, Tezuka H, Oikawa M, Arai F, Asai T, Deng D, Fukuzawa H, Hase M, Hasunuma T, Hayakawa T, Hiraki K, Hiramatsu K, Hoshino Y, Inaba M, Inoue Y, Ito T, Kajikawa M, Karakawa H, Kasai Y, Kato Y, Kobayashi H, Lei C, Matsusaka S, Mikami H, Nakagawa A, Numata K, Ota T, Sekiya T, Shiba K, Shirasaki Y, Suzuki N, Tanaka S, Ueno S, Watarai H, Yamano T, Yazawa M, Yonamine Y, Di Carlo D, Hosokawa Y, Uemura S, Sugimura T, Ozeki Y, Goda K
Raman image-activated cell sorting
Nat Commun 11: 3452 (2020)

Oka, M., Kobayashi, N., Matsumura, K., Nishio, M., Nakano, K., Okamura, T., Okochi, H., Minamisawa, T., Shiba, K. & Saeki,
New Role for Growth/Differentiation Factor 15 in the Survival of Transplanted Brown Adipose Tissues in Cooperation with Interleukin-6
Cells 9: 1365 (2020)

2019年 
Suzuki Y, Kobayashi K, Wakisaka Y, Deng D, Tanaka S, Huang CJ, Lei C, Sun CW, Liu H, Fujiwaki Y, Lee S, Isozaki A, Kasai Y, Hayakawa T, Sakuma S, Arai F, Koizumi K, Tezuka H, Inaba M, Hiraki K, Ito T, Hase M, Matsusaka S, Shiba K, Suga K, Nishikawa M, Jona M, Yatomi Y, Yalikun Y, Tanaka Y, Sugimura T, Nitta N, Goda K, Ozeki Y
A Novel System to Detect Circulating Tumor Cells Using Two Different Size-selective Microfilters
Proc Natl Acad Sci USA 116: 15842-15848 (2019)

Matsumura S, Minamisawa T, Suga K, Kishita H, Akagi T, Ichiki T, Ishikawa Y, Shiba K
Subtypes of tumour cell-derived small extracellular vesicles having differently externalized phosphatidylserine
J Extracell Vesicles 8: 1579541 (2019)

Théry C, et al.
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
J Extracell Vesicles 7: 1535750 (2018)

2018年 
Nitta N, Sugimura T, Isozaki A, Mikami H, Hiraki K, Sakuma S, Iino T, Arai F, Endo T, Fujiwaki Y, Fukuzawa H, Hase M, Hayakawa T, Hiramatsu K, Hoshino Y, Inaba M, Ito T, Karakawa H, Kasai Y, Koizumi K, Lee S, Lei C, Li M, Maeno T, Matsusaka S, Murakami D, Nakagawa A, Oguchi Y, Oikawa M, Ota T, Shiba K, Shintaku H, Shirasaki Y, Suga K, Suzuki Y, Suzuki N, Tanaka Y, Tezuka H, Toyokawa C, Yalikun Y, Yamada M, Yamagishi M, Yamano T, Yasumoto A, Yatomi Y, Yazawa M, Di Carlo D, Hosokawa Y, Uemura S, Ozeki Y, Goda K
Intelligent image-activated cell sorting
Cell 175: 266-276 e13 (2018)

 

 

(作業中)

 

2013年 
Yuasa K, Kokubu E, Kokubun K, Matsuzaka K, Shiba K, Kashiwagi K, Inoue T
An artificial fusion protein between BMP-2 and TBP is functional in vivo
J Biomed Mater Res A: 2013 Apr 27. doi: 10.1002/jbm.a.34765. [Epub ahead of print] (2013)

伊藤正紀、林和美、本間定、芝清隆
細胞性免疫を誘導する人工タンパク質ワクチンの開発
P東京慈恵会医科大学雑誌 128(6): 204-204 (2013)

総説・解説など

 

2012年 
Kobayashi M, Tomita S, Sawada K, Shiba K, Yanagi H, Yamashita I, Uraoka Y
Chiral meta-molecules consisting of gold nanoparticles and genetically engineered tobacco mosaic virus
Optics Express 20(22): 24856-24863 (2012)

 
2011年 
Hashimoto K, Yoshinari M, Matsuzaka K, Shiba K, Inoue T
Identification of peptide motif that binds to the surface of zirconia
Dental Materials Journal 30(6): 935-940 (2011)

Inoue I, Zheng B, Watanabe K, Ishikawa Y, Shiba K, Yasueda H, Uraoka Y, Yamashita I
A novel bifunctional protein supramolecule for construction of carbon nanotube-titanium hybrid material
Chem Comm 47(47): 12649-12651 (2011)

Matsumura S, Aoki I, Saga T, Shiba K
A tumor-environment-responsive nanocarrier that evolves its surface properties upon sensing matrix metalloproteinase-2 and initiates agglomeration to enhance T2 relaxivity for magnetic resonance imaging
Mol Pharm 8(5): 1970-1974 (2011)

Murakami T, Kashiwagi K, Shiba K
Creation of novel signalling modulators from existing cytokine using scanning motif-programming
Chem Comm 47(33): 9357-9359 (2011)

Kasai T, Matsumura S, Iizuka T, Shiba K, Kanamori T, Yudasaka M, Iijima S, Yokoyama A
Carbon nanohorns accelerate bone regeneration in rat calvarial bone defect
Nanotechnol 22: 065102 (8pp) (2011)

Tsuji T, Onuma K, Yamamoto A, Iijima M, Shiba K
Physicochemical properties of artificial proteins that accelerate nucleation of crystalline calcium phosphate
J Cryst Growth 314: 190–195 (2011)

 
2010年 
Tsuji T, Oaki Y, Yoshinari M, Kato T, Shiba K
Motif-programmed artificial proteins mediated nucleation of octacalcium phosphate on the titanium substrates
Chem Comm 46(36): 6675-6677 (2010)

Ikemi M, Kikuchi T, Matsumura S, Shiba K, Sato S, Fujita M
Peptide-coated, self-assembled M12L24 coordination spheres and their immobilization onto an inorganic surface
Chem Sci 1 : 68-71 (2010)

Sano K, Minamisawa T, Shiba K
Autonomous silica encapsulation and sustained release of anticancer protein
Langmuir 26(4) : 2231-2234 (2010)

総説・解説など

佐野健一、芝 清隆
バイオミネラリゼーション研究の新展開ーミネラルの形成と溶解を制御するー
バイオサイエンスとインダストリー 68(5): 336-340(2010)
Shiba K
Exploitation of peptide motif sequences and their use in nanobiotechnology
Curr Opin Biotechnol 21: 412–425 (2010)
Shiba K
Natural and artificial peptide motifs: their origins and the application of motif-programming
Chem Soc Rev 39(1): 117-126 (2010)
 
2009年 
Hayashi T, Sano K, Shiba K, Iwahori K, Yamashita I, Hara M
Critical amino acid residues for the specific binding of the Ti-recognizing recombinant ferritin with oxide surfaces of titanium and silicon
Langmuir 25(18): 10901-10906 (2009)

Patwardhan P, Shiba K, Gordon C, Craddock BP, Minamisawa T, Miller WT
Synthesis of functional signaling domains by combinatorial polymerization of phosphorylation motifs
ACS Chem Biol 4(9): 751-758 (2009)

Yoshinari M, Kato T, Matsuzaka K, Hayakawa T, Shiba K
Prevention of biofilm formation on titanium surfaces modified with conjugated molecules comprised of antimicrobial and titanium-binding peptides
Biofouling 26(1): 103-110 (2009)

Matsukawa N, Nishio K, Sano K, Shiba K, Yamashita I
Hexagonal close-packed array formed by selective adsorption onto hexagonal patterns
Langmuir 25(6): 3327–3330 (2009)

Miyawaki J, Matsumura S, Yuge R, Murakami T, Sato S, Tomida A, Tsuruo T, Ichihashi T, Fujinami T, Irie H, Tsuchida K, Iijima S, Shiba K, Yudasaka M
Biodistribution and ultrastructural localization of single-walled carbon nanohorns determined in vivo with embedded Gd2O3 labels
ACS Nano 3(6): 1399-1406 (2009)

Chirila TV, Minamisawa T, Keen I, Shiba K
Effect of motif-programmed artificial proteins on the calcium uptake in a synthetic hydrogel
Macromol Biosci 9(10): 959-967 (2009)

Matsumura S, Sato S, Yudasaka M, Tomida A, Tsuruo T, Iijima S, Shiba K
Prevention of carbon nanohorn agglomeration using a conjugate composed of comb-shaped polyethylene glycol and a peptide aptamer
Molecular Pharmaceutics 6(2): 441-447 (2009)

Kashiwagi K, Tsuji T, Shiba K
Directional BMP-2 for functionalization of titanium surfaces
Biomaterials 30(6): 1166-1175 (2009)

総説・解説など

芝 清隆
モチーフ・プログラムド人工タンパク質の医療分野での応用
YAKUGAKU ZASSHI 129(11): 1295-1303 (2009)

柏木健司、芝 清隆
階層的進化を模した人工タンパク質の創製
超分子サイエンス&テクノロジー 基礎からイノベーションまで 国武豊喜(監修)エヌティーエス, 1000-1008 (2009)
芝 清隆
がん治療におけるペプチド・アプタマーとナノキャリアの役割
癌と化学療法 36(3): 362-365 (2009)
芝 清隆
モチーフをユニットとした人工分子の創製
実践ゲノムの最前線 井村裕夫(監修) 六然社 : 146-148 (2009)

 
2008年 
Ikezoe Y, Kumashiro Y, Tamada K, Matsui T, Yamashita I, Shiba K, Hara M
Giant growth of two-dimensional crystal of protein molecules from a three-phase contact line
Langmuir 24(22): 12836-12841 (2008)

Tsuji T, Onuma K, Yamamoto A, Iijima Y, Shiba K
Direct transformation from amorphous to crystalline calcium phosphate facilitated by motif-programmed artificial proteins
Proc Natl Acad Sci USA 105(44): 16866-16870 (2008)

Sano K, Shiba K
Stepwise accumulation of layers of aptamer-ornamented ferritins using biomimetic Layer-By-Layer (BioLBL)
J Mater Res: 23 (12): 3236-40 (2008)

Kokubun K, Kashiwagi K, Yoshinari M, Inoue T, Shiba K
Motif-programmed artificial extracellular matrix
Biomacromolecules 9(11): 3098-3105 (2008)

Ishikawa K, Yamada K, Kumagai S, Sano K, Shiba K, Yamashita I, Kobayashi M
Adsorption properties of a gold-binding peptide assessed by its attachment to a recombinant apoferritin molecule
Applied Physics Express 1(3): 034006 (2008)

Saito H, Minamisawa T, Yamori T, Shiba K
Motif-programmed artificial protein induces apoptosis in several cancer cells by disrupting mitochondria
Cancer Science 99(2): 398-406 (2008)

総説・解説など

河村 秀樹、芝 清隆
無機材料結合ペプチド
応用物理 77(10): 1192-1198 (2008)

芝 清隆
人工ペプチドの分子標的化への利用
がんの分子標的治療 鶴尾 隆(編) 南山堂 :35-40 (2008)

Sano K, Shiba K
In aqua manufacturing of a three-dimensional nanostructure using a peptide aptamer
MRS Bulletin 33(5): 524-529 (2008)

芝 清隆
人工ペプチドによる特異的な無機材料表面認識
Molecular Science 2(1): A0023 (2008)

松村 幸子、湯田坂 雅子、飯島 澄男、芝 清隆
カーボンナノチューブでつくるメディカル・デバイス
バイオナノプロセス-溶液中でナノ構造を作るウエット・ナノテクノロジーの薦め- シーエムシー出版 286-300 (2008)

佐野 健一、芝 清隆
無機材料を標的にしたペプチド・アプタマーの異種界面形成
バイオナノプロセス-溶液中でナノ構造を作るウエット・ナノテクノロジーの薦め- シーエムシー出版 92-103 (2008)

河村 秀樹、三浦 篤志、芝 清隆、山下 一郎
バイオナノプロセスをめぐる世界の動き
バイオナノプロセス-溶液中でナノ構造を作るウエット・ナノテクノロジーの薦め- シーエムシー出版 6-21 (2008)


2007年 
Sano K, Yoshii S, Yamashita I, Shiba K
In aqua structuralization of a three-dimensional configuration using biomolecules
Nano Letters 7(10) : 3200-3202 (2007)

Saito H, Kashida S, Inoue T, Shiba K
The role of peptide motifs in the evolution of a protein network
Nucleic Acid Res 35(19): 6357-6366 (2007)

Shiba K, Minamisawa T
A synthesis approach to understanding repeated peptides conserved in mineralization proteins
Biomacromolecules 8(9) : 2659-2664 (2007)

Matsumura S, Ajima K, Yudasaka M, Iijima S, Shiba K
Dispersion of cisplatin-loaded carbon nanohorns with a conjugate comprised of an artificial peptide aptamer and polyethylene glycol
Mol Pharm 4(5) : 723-729 (2007)

Matsui T, Matsukawa N, Iwahori K, Sano K, Shiba K, Yamashita I
Direct production of a two-dimensional ordered array of ferritin-nanoparticles on a silicon substrate
Jpn J Appl Phys 46(28): L713-L715 (2007)

Kulp JL III, Minamisawa T, Shiba K, Tejani M, Evans JS
Structural properties of an artificial protein that regulates the nucleation of inorganic and organic crystals
Langmuir 23(7): 3857-3863 (2007)

Saito H, Minamisawa T, Shiba K
Motif programming: a microgene-based method for creating synthetic proteins containing multiple functional motifs
Nucleic Acid Res 35(6): e38 (2007)

Sano K, Sasaki H, Shiba K
Conversion of a monodispersed globular protein into an amyloid-like filament by appending an artificial peptide at the N-terminal
Protein Eng Des Sel 20(3): 109-116 (2007)

Matsui T, Matsukawa N, Iwahori K, Sano K, Shiba K, Yamashita I
Realizing a two-dimensional ordered array of ferritin molecules directly on a solid surface utilizing carbonaceous materials-affinity peptides
Langmuir 23(4): 1615 -1618 (2007)

総説・解説など

林 智広、佐野 健一、芝 清隆、岩堀 健治、山下 一郎、原 正彦
原子間力顕微鏡を用いた無機物認識ペプチドのターゲット認識メカニズムの解明
表面科学 28(7): 391-396 (2007)

Patwardhan SV, Shiba K, Schroeder HC, Mueller WEG, Clarson SJ, Perry CC
The role of bioinspired peptide and recombinant proteins in silica polymerization
Tne interaction of 'Silicon' with proteins: Part 2, Science and technology of silicones and silicone-modified materials, Clarson SJ et al ed. 328-347 (2007)

芝 清隆
無機材料結合ペプチド
表面 45(6): 185-199 (2007)

芝 清隆
カーボンナノホーンへの薬剤担持とペプチドによる機能化
ナノカーボンハンドブック 遠藤守信/飯島澄夫(監修)エヌ・ティー・エス: 282-288 (2007)

芝 清隆
人工タンパク質のナノバイオテクノロジーでの利用
ケミカルエンジニヤリング 52(7): 534-538 (2007)

芝 清隆、佐野 健一
無機物結合ペプチド
高分子 56(4): 182-186 (2007)

佐野 健一、芝 清隆
ペプチド-無機材料異種界面構造解析が拓くナノバイオテクノロジー
生物物理 47(2): 139-144 (2007)

芝 清隆、佐野 健一
金属結合ペプチドのミネラリゼーション活性を利用したナノ構造形成
『バイオミネラジゼーションとそれに倣う新機能材料の創製』 加藤隆史(監修) シーエムシー出版:273-287 (2007)

佐野 健一、芝 清隆
ペプチドアプタマーを用いたナノ構造体形成
『自己組織化ナノマテリアル』 国武豊喜(監修) フロンティア出版:267-272 (2007)

Shiba K
Nanotubes, nanowires, nanocantilevers and nanorods in cancer treatment and diagnosis
Nanomaterials for cancer diagnosis- Nanotechnologies for the life siciences vol 7- Kumar, CSSR ed. 285-303 (2007)


2006年 
Yamashita I, Kirimura H, Okuda M, Nishio K, Sano K, Shiba K, Hayashi T, Hara M, Mishima Y
Selective nanoscale positioning of ferritin and nanoparticles by means of target-specific peptides
Small 2(10): 1148-1152 (2006)

Murakami T, Fan J, Yudasaka M, Iijima S, Shiba K
Solubilization of single-wall carbon nanohorns using a PEG-doxorubicin conjugate
Mol Pharmaceutics 3(4): 407-414 (2006)

Hayashi T, Sano K, Shiba K, Kumashiro Y, Iwahori K, Yamashita I, Hara M
Mechanism underlying specificity of proteins targeting inorganic materials
Nano Lett 6(3): 515-519 (2006)

Sano K, Sasaki H, Shiba K
Utilization of the pleiotropy of a peptidic aptamer to fabricate heterogeneous nano-dot-containing multilayer nanostructures
J Am Chem Soc 128(5): 1717-1722 (2006)

Kashiwagi K, Isogai Y, Nishiguchi K, Shiba K
Frame shuffling: a novel method for in vitro protein evolution
Protein Eng Des Sel 19(3): 135-140 (2006)

総説・解説など

芝 清隆
結晶成長を人工タンパク質で制御する
日本結晶成長学会誌 33(5):381-387 (2006)

Shiba K
Functionalization of carbon nanomaterials by evolutionary molecular engineering: potential application in drug delivery system
J Drug Target 14(7):512-8 (2006)

芝 清隆
進化分子工学的手法による機能の創出ー無機物結合ペプチド・アプタマーとバイオナノテクノロジー
化学と工業59(8): 852-855 (2006)

佐野 健一、芝 清隆
バイオミネラリゼーションを利用したナノ多層薄膜作製法「BioLBL」
工業材料54(5): 78-81 (2006)

芝 清隆
バイオと無機マテリアルの結合-分子進化工学で得られた無機材料結合性ペプチド-
表面科学27(3): 164-169 (2006)

佐野 健一、芝 清隆
人工ペプチドを利用したナノ多層薄膜形成法
Bionics 3(4): 72-73 (2006)

齊藤 博英、芝 清隆
合成生物学の医療展開
Bionics3(3): 40-45 (2006)

芝 清隆、湯田坂 雅子、飯島 澄男
新規ナノ粒子による薬物担体
日本臨床 64(2): 239-246 (2006)


2005年 
Ajima K, Yudasaka M, Murakami T, Maigne A, Shiba K, Iijima S
Carbon nanohorns as anticancer drug carriers
Mol Pharmaceutics 2(6): 475-480 (2005)

Kulp JL III, Shiba K, Evans JS
Probing the conformational features of a phage display polypeptide sequence directed against single wall carbon nanohorn surfaces
Langmuir 21(25): 11907-11914 (2005)

Sano K, Ajima K, Iwahori K, Yudasaka M, Iijima S, Yamashita I, Shiba K
Endowing a ferritin-like cage protein with high affinity and selectivity for certain inorganic materials
Small 1 (8-9): 826-832 (2005)

Patwardhan SV, Shiba K, Raab C, Huesing N, Clarson SJ
Protein-mediated bioinspired mineralization
Polymer biocatalysis and biomaterials in ACS symposium series 900 ed. Chang H N and Gross R A, pp150-163 American Chemical Society (2005)

Sano K, Sasaki H, Shiba K
Specificity and biomineralization activities of Ti-binding peptide-1 (TBP-1)
Langmuir 21(7): 3090-3095 (2005) [pdf]

総説・解説など

湯田坂 雅子、村上 達也、安嶋 久美子、宮脇 仁、芝 清隆、飯島 澄男
カーボンナノチューブとカーボンナノホーンのDDS応用
PHARM TECH JAPAN 21(12): 2108-2112 (2005)

芝 清隆
プログラマブル人工タンパク質創製
酵素工学ニュース54: 11-15 (2005)

佐野 健一、芝 清隆
チタン表面に特異的に吸着するペプチドTBP-1 の創出とその利用
まてりあ44: 799-803 (2005)

芝 清隆
遺伝子はどこまで創れるか?
生命化学研究レター19: 3-8 (2005)

村上 達也、湯田坂 雅子、飯島 澄男、芝 清隆
カーボンナノ化合物とペプチド・人工タンパク質複合体素の開発とDDSへの利用
BIO INDUSTRY 11月号: 28-33 (2005)

齊藤 博英、芝 清隆
モチーフ・プログラミング -ペプチドモチーフの組み合わせから人工タンパク質を創出する第二世代進化分子工学-
BIO INDUSTRY 11月号: 15-21 (2005)

佐野 健一、芝 清隆
人工ペプチドによる機能性分子配列制御
BIO INDUSTRY 10月号: 33-39 (2005)

佐野 健一、上塚 洋、大西 洋、芝 清隆
AFMとQCM-Dを用いたチタン結合ペプチドのチタン表面への結合の観察
表面科学26(7): 428-431 (2005)

Shiba K
Glycyl-tRNA synthetase
in Aminoacyl-tRNA Syntehtases eds. Ibba M, Francklyn C, Cusack S. Eurekah/Landes Bioscience (2005)


2004年 
Murakami T, Ajima K, Miyawaki J, Yudasaka M, Iijima S, Shiba K
Drug-loaded carbon nanohorns: adsorption and release of dexamethasone in vitro
Mol Pharmaceutics 1(6): 399-405 (2004) [pdf]

Kase D, Kulp III JL, Yudasaka M, Evans JS, Iijima S, Shiba K
Affinity selection of peptide phage libraries against single-wall carbon nanohorns identifies a peptide aptamer with conformational variability
Langmuir 20(20): 8939-8941 (2004) [pdf]

Ramaswamy K, Saito H, Murakami H, Shiba K, Suga H
Designer ribozymes: programming the tRNA specificity into flexizyme
J Am Chem Soc 126(37): 11454-11455 (2004)

Halwani R, Cen S, Javanbakht H, Saadatmand J, Kim S, Shiba K, Kleiman L
Cellular distribution of lysyl-tRNA synthetase and its interaction with gag during human immunodeficiency virus type 1 assembly
J Viol 78(14): 7553-7564 (2004)

Saito H, Honma T, Minamisawa T, Yamazaki K, Noda T, Yamori T, Shiba K
Synthesis of functional proteins by mixing peptide motifs
Chem Biol 11(6): 765-773 (2004)

(修復)
1999

 

Hou YM, Motegi H, Lipman, RSA, Hamann CS, Shiba K
Conservation of a tRNA core for aminoacylation
Nucl Acids Res 27(24): 4743-4750 (1999)

 

 

Michaels J-EA, Shiba K, Miller WT
Autonomous folding of a C-terminal inhibitory fragment of Escerichia coli isoleucine-tRNA synthetase
Biochimica Biophysica Acta 1433: 103-109 (1999)

 

 

芝 清隆
DNA進化論 ~遺伝情報はいかにして誕生・進化を遂げてきたか~
薬事日報 平成11年7月5日(9160): 22-23

 

 

Park SG, Jung KH, Lee JS, Jo YJ, Motegi H, Kim S, Shiba K
Precursor of pro-apoptotic cytokine modulates aminoacylation activity of tRNA synthetase
J Biol Chem 274(24): 16673-16676 (1999)

 

 

Rho SB, Kim MJ, Lee JS, Seol W, Motegi H, Kim S, Shiba K
Genetic dissection of protein-protein interactions in a multi-tRNA synthetase complex
Proc Natl Acad Sci U S A 96(8): 4488-4493 (1999)

 

 

1998

 

Shiba K, Motegi H, Yoshida M, Noda T
Human asparaginyl-tRNA synthetase: Molecular cloning and the inference of the evolutionary history of Asx-tRNA synthetase family
Nucl Acids Res 26(22): 5045-5051 (1998)

 

 

Chihade JW, Hayashibara H, Shiba K, Schimmel P
Strong selective pressure to use G:U to mark an RNA acceptor stem for alanine
Biochemistry 37(25): 9193-9202 (1998)

 

 

Stehlin C, Burke B, Liu H, Shiba K, Musier-Forsyth K
Species-specific differences in the operational RNA code for aminoacylation of tRNAPro
Biochemistry 37(23): 8605-8613 (1998)

 

 

Kim S, Jo Y -J, Lee SH, Shiba K, Motegi H, Sassanfar M, Martinis SA
Biochemical and phylogenetic analyses of methionyl-tRNA synthetase isolated from a pathogenic microorganism, Mycobacterium tuberculosis.
FEBS lett 427(2): 259-262 (1998)

 

 

Shiba K
In vitro constructive approaches to the origin of coding sequences
J Biochem Mol Biol 31(3): 209-220 (1998)

 

 

芝 清隆
アミノアシルtRNA合成酵素から見たゲノム形成のダイナミクス
細胞工学 17(5): 771-780 (1998)

 

 

芝 清隆
試験管の中での遺伝子の誕生
アカデミア 173(1): 34-44 (1998)

 

 

1997

 

芝 清隆
遺伝子を創る - 遺伝子誕生の謎に分子進化工学が迫る
科学 67(12): 938-947 (1997)

 

 

芝 清隆
今がチャンス!
生物物理 37: 147 (1997)

 

 

Shiba K, Motegi H, Schimmel P
Maintaining genetic code through adaptations of tRNA synthetases to taxonomic domains
Trends Biochem Sci 22(12): 453-457 (1997)

 

 

Shibata H, Toyama K, Shioya H, Ito M, Hirota M, Hasegawa S, Matsumoto H, Takano H, Akiyama T, Toyoshima K, Kanamaru R, Kanegae Y, Saito I, Nakamura Y, Shiba K, Noda T
Rapid colorectal adenoma formation initiated by conditional targeting of the Apcgene
Science 278(5335): 120-123 (1997)

 

 

芝 清隆
DNAに秘められた進化のなぞ
Newton 17 (11) (1997)

 

 

Shiba K, Stello T, Motegi H, Musier-Forsyth K, Noda T, Shimmel P
Human lysyl-tRNA synthetase accepts nucleotide 73 variants and rescues Escherichia coli double-defective mutant
J Biol Chem 272(36): 22809-22816 (1997)

 

 

Terunuma A, Shiba K, Noda T
A novel genetic system to isolate a dominant negative effector on DNA-binding activity of Oct-2
Nucl Acids Res 25(10): 1984-1990 (1997)

 

 

Shiba K, Takahashi Y, Noda T
Creation of libraries with long open reading frames by polymerization of a microgene
Proc Natl Acad Sci U S A 94(8): 3805-3810 (1997)

 

 

1996

 

芝 清隆
マイクロ遺伝子を組み合わせて新しいタンパク質を創造できるか?
バイオサイエンスとインダストリー 54(12): 863-864 (1996)

 

 

Michaels J-EA, Schimmel P, Shiba K, Miller WT
Dominant negative inhibition by fragments of a monomeric enzyme
Proc Natl Acad Sci U S A 93(25): 14452-14455 (1996)

 

 

Heacock D, Forsyth CJ, Shiba K, Musier-Forsyth K
Synthesis and aminoacyl-tRNA synthetase inhibitory activity of prolyl adenylate analogs
Bioorganic Chemistry 24: 273-289 (1996)  別刷り品切れ

 

 

Rho SB, Lee KH, Kim JW, Shiba K, Jo YJ, Kim S
Interaction between human tRNA synthetases involves repeated sequence elements
Proc Natl Acad Sci U S A 93(19): 10128-10133 (1996)

 

 

Shiba K, Hatada T, Noda T
Combinatorial assembly of micro-genes
Protein Engineering 9: 813-814 (1996)

 

 

Sassanfar M, Kranz JE, Gallant P, Schimmel P, Shiba K
A eubacterial Mycobacterium tuberculosis tRNA synthetase is eukaryote-like and resistant to a eubacterial-specific antisynthetase drug
Biochemistry 35(31): 9995-10003 (1996)

 

 

1995

 

Nakai S, Kawano H, Yudate T, Nishi M, Kuno J, Nagata A, Jishage K, Fujii H, Hamada H, Kawamura K, Shiba K, Noda T
The POU domain transcription factor Brn-2 is required for the determination of specific neuronal lineages in the hypothalamous of the mouse
Genes Dev 9: 3109-3121 (1995)

 

 

Shiba K, Rimpmaster T, Suzuki N, Nichols R, Plotz P, Noda T, Schimmel P
Human alanyl-tRNA synthetase: conservation in evolution of catalytic core and microhelix recognition
Biochemistry 34(33): 10340-10349 (1995)

 

 

Hipps D, Shiba K, Henderson B, Schimmel P
Operational RNA code for amino acids: species-specific aminoacylation of minihelices switched by a single nucleotide
Proc Natl Acad Sci U S A 92(12): 5550-5552 (1995)

 

 

Shiba K
Dissection of an enzyme into two fragments at intron-exon boundaries
in Tracing biological evolution in protein and gene structures: 11-21 Elsevier Science B. V.(1995)

 

 

Ripmaster TL, Shiba K, Henderson B, Schimmel P
Wide cross-species aminoacyl-tRNA synthetase replacement in vivo: yeast cytoplasmic alanine enzyme replaced by human polymyositis serum antigen
Proc Natl Acad Sci U S A 92(11): 4932-4936 (1995)

 

 

Matsuhisa A, Suzuki N, Noda T, Shiba K
Inositol monophosphatase activity from the Escherichia coli suhB gene product
J Bacteriol 177(1): 200-205 (1995)

 

 

1994

 

Shiba K, Schimmel P, Motegi H, Noda T
Human glycyl-tRNA synthetase. Wide divergence of primary structure from bacterial counterpart and species-specific aminoacylation
J Biol Chem 269(47): 30049-30055 (1994)

 

 

Shiba K, Suzuki N, Shigesada K, Namba Y, Schimmel P, Noda T
Human cytoplasmic isoleucyl-tRNA synthetase: selective divergence of the anticodon-binding domain and acquisition of a new structural unit
Proc Natl Acad Sci U S A 91(16): 7435-7439 (1994)

 

 

Matsuhisa A, Kishi Y, Shiba K
A simple staining method for dna and rna blotted on a membrane using a polyethyleneimine-enzyme conjugate
J Biochem 116(3): 478-81 (1994)

 

 

1993 - NO PAPER



1992

 

Schimmel P, Shepard A, Shiba K
Intron locations and functional deletions in relation to the design and evolution of a subgroup of class I tRNA synthetases
Protein Sci 1(10): 1387-91 (1992)

 

 

Shiba K, Schimmel P
Tripartite functional assembly of a large class I aminoacyl tRNA synthetase
J Biol Chem 267(32): 22703-6 (1992)

 

 

Shepard A, Shiba K, Schimmel P
RNA binding determinant in some class I tRNA synthetases identified by alignment-guided mutagenesis
Proc Natl Acad Sci U S A 89(20): 9964-8 (1992)

 

 

Taura T, Ueguchi C, Shiba K, Ito K
Insertional disruption of the nusB (ssyB) gene leads to cold-sensitive growth of Escherichia coli and suppression of the secY24 mutation
Mol Gen Genet 234(3): 429-32 (1992)

 

 

Shiba K, Schimmel P
Functional assembly of a randomly cleaved protein
Proc Natl Acad Sci U S A 89(5): 1880-4 (1992)

 

 

1991

 

Asano K, Kato A, Moriwaki H, Hama C, Shiba K, Mizobuchi K
Positive and negative regulations of plasmid CoLIb-P9 repZ gene expression at the translational level
J Biol Chem 266(6): 3774-81 (1991)

 

 

Hou Y-M, Shiba K, Mottes C, Schimmel P
Sequence determination and modeling of structural motifs for the smallest monomeric aminoacyl-tRNA synthetase
Proc Natl Acad Sci U S A 88(3): 976-80 (1991)

 

 

1990

 

Yano R, Nagai H, Shiba K, Yura T
A mutation that enhances synthesis of sigma 32 and suppresses temperature-sensitive growth of the rpoH15 mutant of Escherichia coli
J Bacteriol 172(4): 2124-30 (1990)

 

 

Shiba K, Mizobuchi, K
Posttranscriptional control of plasmid ColIb-P9 repZ gene expression by a small RNA
J Bacteriol 172(10): 1992-7 (1990)

 

 

1987-1989 ECLIPSE



1986

 

Shiba K, Ito K, Nakamura Y, Dondon J, Grunberg-Manago M
Altered translation initiation factor 2 in the cold-sensitive ssyG mutant affects protein export in Escherichia coli
EMBO J 5(11): 3001-6 (1986)

 

 

Bacallao R, Crooke E, Shiba K, Wickner W, Ito K
The secY protein can act post-translationally to promote bacterial protein export
J Biol Chem 261(27): 12907-10 (1986)

 

 

Ito K, Akiyama Y, Yura T, Shiba K
Diverse effects of the MalE-LacZ hybrid protein on Escherichia coli cell physiology
J Bacteriol 167(1): 201-4 (1986)

 

 

Shiba K, Ito K, Yura T
Suppressors of the secY24 mutation: identification and characterization of additional ssy genes in Escherichia coli
J Bacteriol 166(3): 849-56 (1986)

 

 

1985

 

伊藤 維昭、芝 清隆、秋山 芳展
タンパク質の局在化
細胞工学 4(13): 1172-1184 (1985)

 

 

芝 清隆, 伊藤 維昭
タンパク質の膜透過機構とその遺伝制御
化学と生物 23(3): 186-191 (1985)

 

 

1984

 

Shiba K, Ito K, Yura T
Mutation that suppresses the protein export defect of the secY mutation and causes cold-sensitive growth of Escherichia coli
J Bacteriol 160(2): 696-701 (1984)

 

 

Shiba K, Ito K, Yura T, Cerretti, DP
A defined mutation in the protein export gene within the spc ribosomal protein operon of Escherichia coli: isolation and characterization of a new temperature-sensitive secY mutant
EMBO J 3(3): 631-5 (1984)

 

 

1983

 

Ito K, Wittekind M, Nomura M, Shiba K, Yura T, Miura A, Nashimoto H
A temperature-sensitive mutant of E. coli exhibiting slow processing of exported proteins
Cell 32(3): 789-97(1983)

 

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